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Jawaharlal Nehru Tropical Botanic Garden and Research Institute

Achievements

Achievements at a glance

Patents filed/awarded: 11
Books Published: 6
Handouts Published: 4
Case study: 6
Chapters in books: 47
Research papers: 175
Conferences/ Seminars/ Workshops: 597
Media interactions (AIR/TV): 60
Extension activities: 60
Honours/ Awards: 132
Completed Projects: 34
Ongoing Projects: 6 

 

Technology Transfer

Herbal Drug Developed – Technology Transferred: JEEVANI

Jeevani is a noval health promotive herbal formulation consisting of 4 ingredients perfected after conducting a detailed Ethnopharmacological study and open clinical trial. The technology was transferred to Arya Vaidya Pharmacy (Coimbatore) Ltd. Kanjikode, Kerala, for commercial production. Through this transfer of technology JNTBGRI received Rs. 10 lakhs (Rupees Ten Lakhs) as license fee and 2% Royality on the ex-factory sales price from the company. It hasa immunoenhancing, antifatigue, antistress and hepatoprotective activities.

 

Herbal Drug Developed – Technology Transferred: SISAIROSP (Oil / ointment)

SISAIROSP isisairosp-as an antipsoriatic and antidandruff herbal formulation consisting of 3 ingredients perfected as an external application after conducting Ethnopharmacological study and Clinical trial. The technology was transferred to a Madhya Pradesh based company, sisairosp-bJhawar Chemicals. Through this technology tsisairosp-cransfer JNTBGRI received Rupees Five Lakhs (Rs. 5 Lakhs) as license fee and 2.5% royalty on ex-factory sales price. It is an herbal drug for only external application to get an excellent control over the psoriatic lesions and dandruff.

                                                      

 

Technology Developed:

1. HERBAL HEALTH CARE KIT

It contains safe, effective, inexpensive and eco-friendly herbal remedies. These formulations are the outcome of a unique blend of traditional and Ayurvedic medical knowledge, with that of modern science and technology. It consists of 8 herbal preparations (5 drugs for oral use and 3 for external application.)

ORAL ADMINISTRATION
Name of drug Presentation Indication
TBR 001 Granules Dehydration in Diarrhoea and Vomiting
TBR 002 Capsule Fever
TBR 003 Tablet Diarrhoea, Dysentery
TBR 004 Tablet Gas trouble, Constipation, Intestinal colic
TBR 005 Tablet Cough
EXTERNAL APPLICATION
TBR 0011 TBR 0013 Cuts, Wounds, Minor injuries
TBR 0012 Ointment / Oil Sprain, Inflammation, Dislocation
TBR 0013 Ointment Headache, Common cold

 

2. HERBAL COUGH SYRUP

A safe herbal cough syrup consisting only of 2 ingredients has been developed. It is an effective remedy for cough and cough related with allergic conditions.

 

 

 

 

3. VAJI (Nutraceuticals developed for Sports Personnel’s)

This is a novel and safe herbal formulation (Nutraceutical) developed exclusively for sports personnel’s. Double blind clinical trial was carried out in 30 volley ball players (females) in collaboration with Lekshmibai National Sports School, Government of India, Kariyavattom, Thiruvananthapuram. The study showed encouraging results, especially noted improvements in their performance.

 

 

 

Development of New Herbal Drugs/Nutraceuticals

A novel poly herbal formulation

MoU signed with a Traditional healer (Shri. Shahul Hameed Vaidyar) for conducting preclinical studies of a coded medicinal plant species (222) having anti-diabetic and hepatoprotective properties under the in-house programme.  

 

 

Clinical trial of a coded hepatoprotective poly herbal formulation

MoU signed with Oushadhi (Pharmaceutical Corporation – I.M.) Kerala Ltd., (Govt. of Kerala undertaking) for conducting the clinical trial of coded drug (TBGO-1)

 

 

 

Other important projects

Kani Model of Access and Benefit Sharing

Kani Model of Access and Benefit Sharingis a unique benefit sharing model developed during the year 1996.

The model relates to the development of the scientifically validated herbal drug, ‘Jeevani’, based on a tribal lead obtained from a plant species known as ‘Arogyapacha’ (Trichopus zeylanicus ssp. travancoricus Burkill. ex Narayanan).

Perhaps, this is the first benefit sharing model in the world. This unique benefit sharing model won the ‘UN-Equator Initiative Award’ during the last Earth Summit, in 2002 held at Johannesburg.

           

 

Pilot Participatory Programme on Conservation and Sustainable Use of Medicinal and Aromatic Plants under the Kerala Forestry Programme aided by World Bank

This is a unique multidisciplinary, multidimensional and multisectoral pilot participatory programme of conservation and sustainable use of medicinal and aromatic plants. This project was exclusively designed for the tribal communities for improving their livelihood and capacity building. 

   

 

Herbs for All and Health for All

‘Herbs for All and Health for All’ is a model, experimented by the Division of Ethnomedicine and Ethnopharmacology, with a view to empower the people to take their primary health care needs by making best use of the locally available medicinal and food plant resources. It is essentially a participatory, action-oriented programme. It has been designed to conserve and utilize the plant diversity in a sustainable manner.

  

 

Ethno-medico-botanical survey

Successfully carried out ethno-medico-botanical survey among the Kani and Malapandaram tribes of Kerala.

Mega project proposal entitled ‘Vanasamrakshaneeyam’ (Save the Forest and Save Life) was prepared exclusively for Kerala Forest Department. This project proposes a holistic approach linking forest ecosystem, indigenous knowledge, ayurveda, agriculture, modern Science and technology.

Published a book entitled “Star and Trees” with the financial support of Thenmala Ecotourism Promotion Society, Govt. of Kerala.

  

 

Systematic documentation of plants used for food and medicine

  • Developed a Prior Informed Consent (PIC) for the Systematic documentation of Traditional Knowledge related to plants used for food and medicine.

  • Successfully completed the field level documentation of indigenous knowledge of 15 selected Gramapanchayaths (5 each from Thiruvananthapuram, Kollamand Pathanamthitta districts of Kerala state)
  • Successfully completed the systematic documentation of Indigenous/Traditional Knowledge related to plants used for food and medicine in the selected 5 Gramapamchayaths each in Kasaragod, Kannur, Palakkad and Alappuzha district of Kerala state.
  • Successfully completed the systematic documentation of Traditional Knowledge related to plants used for food and medicine at 70 Gramapanchayaths, 5 each from all 14 districts of Kerala state and we could document 15733, traditional information related to medicinal properties and 650 information related to the culinary properties of our plant diversity. Out of these, 1125 information were documented from the tribal communities. We have interviewed 1297 informants during the course of study.

  • Extended awareness/educational programmes on Biodiversity Conservation, Traditional Knowledge associated Biodiversity, IPR, etc. to the 70 Gramapanchayaths of Kerala state.
  • Prepared a documentary film entitled ‘From Haze……Light!’ (English & Malayalam version) on traditional knowledge related to plants used for food and medicine.

  • Formulated “Indigenous Knowledge Strategies for Kerala” through conducting an exclusive workshop with the support of division of Indigenous Knowledge (IK), World Bank, Washington DC, with a view to incorporate the same in the planning process of Govt. of Kerala.

               

 

Systematic documentation of Traditional Knowledge related to plants used for Food, AYUSH and Indigenous medicine

  • Successfully organized contact and awareness programme including small workshops and seminars at 98 Gramapanchayaths of Kasaragod, Kannur, Kozhikode, Wayanad, Malappuram, Palakkad and Thrissur districts of Kerala state
  • Through the implementation of Activity 1, dissemination extended to more than ten thousand people including elected local body members, knowledge holders on the subject – Biodiversity and associated TK, importance of sector wise TK especially knowledge related to plants used for food and medicine, necessity for the preparation of Gramapanchayath wise Biodiversity Register and its protection and utilization, the role of PIC for the protection and ownership rights of TK, the role PIC in ABS, basic knowledge on conventional IPR regime, protection of TK under Sui generis system, the role of database for the protection of TK and ABS, scope of conducting research based on TK and its potential for developing novel herbal drugs, modern medicine, nutraceuticals and other plant based products and also demonstrated the uses of locally available medicinal and food plants for primary healthcare.
  • Encouraged/motivated the healers to preserve their rich traditional heritage for future generations.
  • Successfully completed the systematic documentation of Traditional Knowledge related to plants used for food and AYUSH & Indigenous medicine of 98 Gramapanchayaths
  • Introduced Prior Informed Consent (PIC).
  • Interviewed 3255 (461 tribes and 2794 non-tribes) knowledge providers and documented a total of 26419 information. Out of which 3392 (12.84%) recorded from different tribal communities and 23027(87.16%) documented from non-tribal communities of various districts brought under the study.
  • The achievement of the third activity includes data pooling, analysis and organization of field data documented from 98 Gramapanchayaths. Based on the single drugs we had documented 14684 information (tribal – 1839 and non-tribal – 12845) and in the poly herbal formulations, 8852information (tribal – 855 and non-tribal – 7997) were documented. Similarly under the food category 2883 information (tribal – 708 and non-tribal – 2175) has been recorded and documented.
  • Carried out the data analysis of diseases and diseased conditions prepared based on the data systematically documented and pooled from 70 Gramapanchayaths aimed to project the district wise utility pattern of medicinal plants either alone or in combination for treating diseases and diseased conditions.
  • Presented 20 selected case studies of Folk/Traditional Medical interventions and Food practices prevalent in Kerala.
  • The script writing of one hour duration documentary film on Traditional Knowledge related to Plants used for Food and AYUSH & Indigenous Medicine is in the final stage and will be released shortly.
  • Successfully developed software which is intended to create a new web based database system for preparing electronic database and digitizing the data collected for the project entitled “Systematic Documentation of Traditional Knowledge related to Plants used for Food, AYUSH & Indigenous Medicine”.
  • Successfully conducted one day workshop on ‘Learning from Traditional Knowledge’ exclusively for AYUSH doctors with an objective to disseminate the importance and value of Traditional knowledge to AYUSH doctors in four districts of Kerala.
  • Publication of the Journal entitled ‘Journal of Traditional and Folk Practices’ is in the final stage and the first issue will be released shortly.
  • ‘Student’s Handbook on Medicinal and Food Plants’ is ready for publication.
  • Published a book entitled ‘Traditional and Folk practices – Contemporary relevance and future prospects’ as part of the training programme extended to AYUSH Doctors.
  • Three publications related to IEC materials is in the final stage and will be published shortly.
  • Successfully organized two training programmes to AYUSH doctors on Traditional/Folk practices at JNTBGRI on the subject ‘Traditional and Folk practices – contemporary relevance and future prospects’.
  • Under Activity 9, we had successfully conducted two training programmes exclusively to AYUSH doctors on traditional/folk practicesat JNTBGRI with a view to create awareness on the subject ‘Traditional and Folk practices – contemporary relevance and future prospects’. The training programme for the first batch was conducted from 24-25, August 2011 and the second batch training was organized from 26-27, August 2011.

               

                

 

AYUSH PUBLICATIONS (Publishing shortly)
 
           
 
 

Consultancy Programme

  • Successfully completed the Pilot participatory program of Conservation and Sustainable use of medicinal and aromatic plants [Kerala Forest Dept. (World Bank Consultancy project)].
  • Carried out Dermal and Ocular toxicity studies of 8 herbal baby care products of the brand Tenderils from Krauter Health Care Ltd. Noida UP. (Amity Institute of Herbal and Biotech Products Development, Trivandrum).

Ethnopharmacological leads obtained:

  1. Hepatoprotective leads obtained from Spilanthes ciliata H.B.K, Helminthostachys zeylanica (L.) Hook, Rhinacanthus nasuta Linn.(Kurz), Pittosporum neelgherrense Wight&Arn, Hedyotis corymbosa (L.) Lam., Sida acuta Burm. f., Hibiscus hispidissimus Griffith., Utleria salicifolia Bedd. Ex. Hook. f., Cyclea peltata (Poiret) Hook. f. &Thomson, Capparis brevispina DC, Ixora coccinea L., Oxalis corniculata L., Thespesia populnea(L.).
  2. Anti-tumour activity obtained from Ixora coccinea L, Psoralea corylifolia L., Elephantopus scaber Linn.
  3. Anti-inflammatory and analgesic activities obtained from Ficus religiosa L., Clerodendron infortunatum Linn, Naravelia zeylanica (L.) DC, Vitex altissima L., Drynaria quercifolia (L.) J. Smith, Kaempferia rotunda Linn., Justicia gendarussa Burm.f., Barringtonia racemosa (L.) Sprengel, Commiphora caudata (Wight &Arn.)Engl., Cassia occidentalis Linn., Rhaphidophora pertusa (Roxb.) Schott, Wattakaka volubilis (L.f.) Stapf., Erythrina indica Lam., Mimusops elengi Linn., Lepianthes umbellata (L.)Raf., Cissampelos pareira L., Epipremnum pinnatum (L.)Engl. CV. Aureum.
  4. Anti-Diabetic activities obtained from Tinospora cordifolia (Willd.) Miers ex Hook. f. &Thomson, Withania coagulans (L.)Dunal, Pisonia alba Span., Smilax zeylanica L., Pilea microphylla (L.) Liebm, Plumbago rosea L., Caesalpinia pulcherrima (L.) Sw.
  5. Wound healing activities obtained from Kaempferia rotunda L., Glycosmis pentaphylla (Retz.) DC.
  6. Anti-ulcer activities obtained from Cyclea peltata (Poiret) Hook. F. & Thomson.
  7. Anti-diarrhoeal activity obtained from Erythrina indica Lam.
  8. Anti-fatigue, anti-tumour, anti-gastric ulcer, anti-stress, anti-allergic, anti-oxidant, adaptogenic, aphrodisiac, immunomodulatory, hepatoprotective, and antioxidant obtained from Trichopus zeylanicus ssp. Travancoricus Burkill ex Narayanan.
  9. Anti-tumor, immunomodulatory and ulcerogenic effect obtained from Janakia arayalpatra (Joseph & V Chandras.)

 

 

 

 

 

 

 

 

 

 

                                                                                                                                                                                                       

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